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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
23.33
Human Site:
Y538
Identified Species:
39.49
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
Y538
Y
N
I
L
T
H
D
Y
G
T
K
G
D
S
P
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
Y538
Y
N
I
L
T
H
D
Y
G
T
K
G
D
S
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
Y635
Y
N
I
L
T
H
D
Y
G
T
K
G
D
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
Y532
Y
N
I
L
T
H
D
Y
G
T
K
D
D
S
P
Rat
Rattus norvegicus
NP_001099948
974
110023
Y503
Y
N
I
L
T
H
D
Y
G
T
K
D
N
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
T493
D
R
E
W
W
H
R
T
I
Q
R
P
V
T
M
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
Y528
Y
S
V
L
S
S
D
Y
G
S
R
S
E
S
P
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
S518
K
A
V
L
E
L
Q
S
E
R
R
W
I
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
H586
Y
Q
I
V
A
R
E
H
K
S
L
S
A
V
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
E614
T
Y
S
T
V
A
A
E
F
K
A
K
Q
K
A
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
F408
A
F
L
R
F
E
P
F
S
I
K
S
Y
W
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
I490
L
R
F
E
P
F
S
I
K
S
Y
W
Q
S
L
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
C399
D
R
M
H
C
D
H
C
S
H
V
I
M
Q
H
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
G696
D
V
I
I
T
S
Y
G
V
V
L
S
E
F
T
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
86.6
N.A.
6.6
N.A.
46.6
6.6
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
20
N.A.
86.6
20
N.A.
40
N.A.
N.A.
0
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
6.6
N.A.
N.A.
6.6
0
13.3
P-Site Similarity:
20
N.A.
N.A.
13.3
6.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
8
8
0
0
0
8
0
8
0
8
% A
% Cys:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
22
0
0
0
0
8
43
0
0
0
0
15
29
0
0
% D
% Glu:
0
0
8
8
8
8
8
8
8
0
0
0
15
0
0
% E
% Phe:
0
8
8
0
8
8
0
8
8
0
0
0
0
8
8
% F
% Gly:
0
0
0
0
0
0
0
8
43
0
0
22
0
0
0
% G
% His:
0
0
0
8
0
43
8
8
0
8
0
0
0
0
8
% H
% Ile:
0
0
50
8
0
0
0
8
8
8
0
8
8
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
15
8
43
8
0
8
0
% K
% Leu:
8
0
8
50
0
8
0
0
0
0
15
0
0
8
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
36
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
8
0
8
0
0
0
0
8
0
0
43
% P
% Gln:
0
8
0
0
0
0
8
0
0
8
0
0
15
8
8
% Q
% Arg:
0
22
0
8
0
8
8
0
0
8
22
0
0
0
0
% R
% Ser:
0
8
8
0
8
15
8
8
15
22
0
29
0
50
8
% S
% Thr:
8
0
0
8
43
0
0
8
0
36
0
0
0
8
8
% T
% Val:
0
8
15
8
8
0
0
0
8
8
8
0
8
8
0
% V
% Trp:
0
0
0
8
8
0
0
0
0
0
0
15
0
8
0
% W
% Tyr:
50
8
0
0
0
0
8
43
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _